| Saturday, 14/03/1981 | Coburg - Heidelberg | 1:1 | ||||||
| Saturday, 21/03/1981 | Bell Park - Coburg | 4:0 | ||||||
| Saturday, 28/03/1981 | Coburg - Port Melbourne | 1:1 | ||||||
| Saturday, 04/04/1981 | St Albans Saints - Coburg | 2:1 | ||||||
| Saturday, 11/04/1981 | Coburg - Prahran City | 3:2 | ||||||
| Saturday, 18/04/1981 | Eltham - Coburg | 3:2 | ||||||
| Saturday, 25/04/1981 | Coburg - Corio | 1:3 | ||||||
| Saturday, 02/05/1981 | Werribee City - Coburg | 1:3 | ||||||
| Saturday, 09/05/1981 | Ringwood United - Coburg | 4:1 | ||||||
| Saturday, 23/05/1981 | Coburg - Yallourn | 1:1 | ||||||
| Saturday, 30/05/1981 | Broadmeadows City - Coburg | 1:0 | ||||||
| Saturday, 06/06/1981 | Heidelberg - Coburg | 0:0 | ||||||
| Saturday, 13/06/1981 | Coburg - Bell Park | 1:2 | ||||||
| Saturday, 20/06/1981 | Port Melbourne - Coburg | 2:0 | ||||||
| Saturday, 27/06/1981 | Coburg - St Albans Saints | 1:2 | ||||||
| Saturday, 04/07/1981 | Prahran City - Coburg | 1:2 | ||||||
| Saturday, 11/07/1981 | Coburg - Eltham | 1:1 | ||||||
| Saturday, 18/07/1981 | Corio - Coburg | 0:0 | ||||||
| Saturday, 25/07/1981 | Coburg - Werribee City | 0:1 | ||||||
| Saturday, 01/08/1981 | Coburg - Ringwood United | 1:0 | ||||||
| Saturday, 08/08/1981 | Yallourn - Coburg | 1:1 | ||||||
| Saturday, 15/08/1981 | Coburg - Broadmeadows City | 3:1 |